abstract：BACKGROUND:Emotion recognition plays a key role in multimedia. To enhance the sensation of reality, smell has been incorporated into multimedia systems because it can directly stimulate memories and trigger strong emotions. NEW METHOD:For the recognition of olfactory-induced emotions, this study explored a combination...

journal_title：Journal of neuroscience methods

authors： Hou HR,Zhang XN,Meng QH

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:To increase power when analyzing fMRI data, researchers often define functional regions of interest (fROIs). It is crucial that this fROI is defined with an optimal balance between both false positives and false negatives to ensure maximal spatial accuracy and to avoid potentially biased results in the main ...

journal_title：Journal of neuroscience methods

authors： Degryse J,Moerkerke B

更新日期：2020-01-15 00:00:00

abstract：BACKGROUND:Mechanical properties of the brain tissue are crucial to understand the mechanisms of traumatic brain injury (TBI). Injured brain tissue could induce changes of mechanical properties and anatomical structures. However, limited data is available for the injured tissue. NEW METHOD:We developed a custom-built ...

journal_title：Journal of neuroscience methods

authors： Qiu S,Jiang W,Alam MS,Chen S,Lai C,Wang T,Li X,Liu J,Gao M,Tang Y,Li X,Zeng J,Feng Y

更新日期：2020-01-15 00:00:00

abstract：:Modern clearing techniques enable high resolution visualization and 3D reconstruction of cell populations and their structural details throughout large biological samples, including intact organs and even entire organisms. In the past decade, these methods have become more tractable and are now being utilized to provi...

journal_title：Journal of neuroscience methods

authors： Porter DDL,Morton PD

更新日期：2020-01-13 00:00:00

abstract：BACKGROUND:Cortico-Cortical Evoked Potentials (CCEPs) are a novel low frequency stimulation method used for brain mapping during intracranial epilepsy investigations. Only a handful of metrics have been applied to CCEP data to infer connectivity, and no comparison as to which is best has been performed. NEW METHOD:We ...

journal_title：Journal of neuroscience methods

authors： Prime D,Woolfe M,Rowlands D,O'Keefe S,Dionisio S

更新日期：2020-01-09 00:00:00

abstract：BACKGROUND:Photothrombosis is a minimally invasive method for induction of cortical ischemia. However, different ways of applying some methods to assess photothrombosis-induced damage need to be developed. NEW METHODS:We applied the tongue protrusion test and H&E staining of brain sections to detect ischemic damage af...

journal_title：Journal of neuroscience methods

authors： Galkov M,Gulyaev M,Kiseleva E,Andreev-Andrievskiy A,Gorbacheva L

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Primary cell culture is a valuable tool to utilize in parallel with in vivo studies in order to maximize our understanding of the mechanisms surrounding neurogenesis and central nervous system (CNS) regeneration and plasticity. The zebrafish is an important model for biomedical research and primary neural ce...

journal_title：Journal of neuroscience methods

authors： Patel BB,Clark KL,Kozik EM,Dash L,Kuhlman JA,Sakaguchi DS

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Contralateral seventh cervical nerve transfer (contralateral C7 transfer) is a novel treatment for patients with spastic paralysis, including stroke and traumatic brain injury. However, little is known on changes in plasticity that occur in the intact hemisphere after C7 transfer. An appropriate surgical mod...

journal_title：Journal of neuroscience methods

authors： Ye X,Shen YD,Feng JT,Wang F,Gao ZR,Lei GW,Yu AP,Wang CP,Liang CM,Xu WD

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Traumatic brain injury (TBI) includes primary and secondary injuries, while monitoring intracranial pressure (ICP) and cerebral blood flow (CBF) is conducive to improve the prognosis of patients. However, the function of cerebral venous in this process is still unclear. NEW METHOD:An acute epidural hematoma...

journal_title：Journal of neuroscience methods

authors： Wang W,Mu S,Xue L,Liang S,Li Z,Wang S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Transcranial magnetic stimulation (TMS) can be paired with functional magnetic resonance imaging (fMRI) in concurrent TMS-fMRI experiments. These multimodal experiments enable causal probing of network architecture in the human brain which can complement alternative network mapping approaches. Critically, me...

journal_title：Journal of neuroscience methods

authors： Oh H,Kim JH,Yau JM

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Within a circuit, specific neurons and synapses are hypothesized to have essential roles in circuit physiology and learning, and dysfunction in these neurons and synapses causes specific disorders. These critical neurons and synapses are embedded in complex circuits containing many neuron and synapse types. ...

journal_title：Journal of neuroscience methods

authors： Nagayach A,Singh A,Geller AI

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Compared to previous neuropsychological investigations with standard paper-pen tests limited to test complex spatial learning and memory processes, 3-D virtual immersive technology might offer new tools for research purposes and for diagnosis in patients suffering from mild cognitive impairment or dementia. ...

journal_title：Journal of neuroscience methods

authors： Machado ML,Lefèvre N,Philoxene B,Le Gall A,Madeleine S,Fleury P,Smith PF,Besnard S

更新日期：2019-11-01 00:00:00

abstract：:Electrophysiology is the study of neural activity in the form of local field potentials, current flow through ion channels, calcium spikes, back propagating action potentials and somatic action potentials, all measurable on a millisecond timescale. Despite great progress in imaging technologies and sensor proteins, no...

journal_title：Journal of neuroscience methods

authors： Suk HJ,Boyden ES,van Welie I

更新日期：2019-10-01 00:00:00

abstract：:Since the advent of optogenetics, the technology development has focused on new methods to optically interact with single nerve cells. This gave rise to the field of photonic neural interfaces, intended as the set of technologies that can modify light radiation in either a linear or non-linear fashion to control and/o...

journal_title：Journal of neuroscience methods

authors： Pisano F,Pisanello M,De Vittorio M,Pisanello F

更新日期：2019-09-01 00:00:00

abstract：:An understanding of how the brain processes information requires knowledge of its underlying wiring diagrams, as well as insights into the relationship between circuit architecture and physiological function. Notably, rabies virus based single-cell genetic manipulations that can facilitate an experimental link between...

journal_title：Journal of neuroscience methods

authors： Schwarz MK,Remy S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Local shape complexity can be biologically meaningful as a marker of disease, trauma, or change in brain structure over time. Fractal dimensionality (FD) is currently the dominant measure of local shape complexity used in neuroimaging but its limitations are not well understood. NEW METHOD:Elliptical Fourie...

journal_title：Journal of neuroscience methods

authors： Walsh EI,Zhang T,Cherbuin N

更新日期：2019-07-15 00:00:00

abstract：BACKGROUND:Zebrafish (Danio rerio) are growing in popularity as a vertebrate model organism for the study of spinal neurocircuitry and locomotion. While many studies have used the zebrafish model system for electrophysiological analyses in embryonic and larval stages, there is a growing interest in studying spinal circ...

journal_title：Journal of neuroscience methods

authors： Meade ME,Roginsky JE,Schulz JR

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Temporal changes of pain perception to prolonged tonic heat pain are conventionally assessed using a computerized visual analog scale. Such a rating-based approach is, however, prone to floor and ceiling effects, which limit the assessment of temporal changes in perception. Thus, alternative methods that ove...

journal_title：Journal of neuroscience methods

authors： Jutzeler CR,Sirucek L,Scheuren PS,Bobo T,Anenberg E,Ortiz O,Rosner J,Hubli M,Kramer JLK

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Neurotrauma patients face major neurological sequelae. The failure in the preclinical-to-clinical translation of candidate therapies could be due to poor evaluation of rodent behaviours after neurotrauma. NEW METHOD:A home cage automated system was used to study the long term behaviour of individual rats wi...

journal_title：Journal of neuroscience methods

authors： Yip PK,Chapman GE,Sillito RR,Ip THR,Akhigbe G,Becker SC,Price AW,Michael-Titus AT,Armstrong JD,Tremoleda JL

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Recently, hybrid brain-computer interfaces (BCIs) combining more than one modality have been investigated with the aim of boosting the performance of the existing single-modal BCIs in terms of accuracy and information transfer rate (ITR). Previously, we introduced a novel hybrid BCI in which EEG and fTCD mod...

journal_title：Journal of neuroscience methods

authors： Khalaf A,Sejdic E,Akcakaya M

更新日期：2019-05-15 00:00:00

abstract：BACKGROUND:Primary astrocyte cultures have been used for decades to study astrocyte functions in health and disease. The current primary astrocyte cultures are mostly maintained in serum-containing medium which produces astrocytes with a reactive phenotype as compared to in vivo quiescent astrocytes. The aim of this st...

journal_title：Journal of neuroscience methods

authors： Prah J,Winters A,Chaudhari K,Hersh J,Liu R,Yang SH

更新日期：2019-05-15 00:00:00

abstract：BACKGROUND:Currently, assessment of unmyelinated axon regeneration is limited to electron microscopy (EM), which is expensive, time consuming and not universally available. This study presents a protocol to estimate the number of unmyelinated axons in a regenerating peripheral nerve without the need for electron micros...

journal_title：Journal of neuroscience methods

authors： Hendry JM,Alvarez-Veronesi MC,Chiang C,Gordon T,Borschel GH

更新日期：2019-05-15 00:00:00

abstract：BACKGROUND:Events that instigate disease may involve biochemical events distinct from changes in the steady-state levels of proteins. Even chronic degenerative disorders appear to involve changes such as post-translational modifications. NEW METHOD:We have begun a series of proteomics analyses on proteins that have be...

journal_title：Journal of neuroscience methods

authors： Ayyadevara S,Ganne A,Hendrix RD,Balasubramaniam M,Shmookler Reis RJ,Barger SW

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:This manuscript describes a new, multidimensional and data-driven approach to identify outlying datapoints from a first-level fMRI dataset. NEW METHOD:Using three different indicators of data corruption (the fast variance component of DVARS [Δ%D-var], scan-to-scan total displacement [STS], and each scan's o...

journal_title：Journal of neuroscience methods

authors： Wilke M,Baldeweg T

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:Assessing markers of neural activity in rodent behavioural tasks benefits from meaningful comparison with matched control conditions. The Morris water maze is a widely used learning and memory task, but currently implemented control conditions are not optimal. NEW METHOD:We created a novel control condition...

journal_title：Journal of neuroscience methods

authors： Barry DN,Commins S

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:To establish a novel rat model of middle cerebral artery occlusion (MCAO) complicated with prior venous stagnation, and to investigate the role of cerebral venous drainage in neural injury after acute cerebral infarction. NEW METHOD:Eighteen SD rats were randomly divided into two groups: control group and j...

journal_title：Journal of neuroscience methods

authors： Zhang NN,Zhao KT,Zhao ZA,Chen WL,Xu HB,Chen HS

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:Glucose hypermetabolism in denervated skeletal muscle suggests the potential for developing a diagnostic tool for peripheral nerve injuries. Herein, we investigated the characteristics and molecular mechanism of this phenomenon. NEW METHOD:Temporal course of glucose hypermetabolism and development of abnorm...

journal_title：Journal of neuroscience methods

authors： Lee SH,Seo HG,Oh BM,Choi H,Cheon GJ,Lee SU

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The classification of sleep signals is a subjective and time consuming task. A large number of automatic classifiers have been published in the past decade but a sleep community has no strong confidence to use them in clinical practice and still remains using a standard manual scoring according standardized ...

journal_title：Journal of neuroscience methods

authors： Gerla V,Kremen V,Macas M,Dudysova D,Mladek A,Sos P,Lhotska L

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Translational studies investigating the effects of deep brain stimulation (DBS) on brain function up to now mainly relied on BOLD responses measured with fMRI. However, fMRI studies in rodents face technical and practical limitations (e.g., immobilization, sedation or anesthesia, spatial and temporal resolut...

journal_title：Journal of neuroscience methods

authors： Bazzu G,Serra PA,Hamelink R,Feenstra MGP,Willuhn I,Denys D

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:It has previously been reported that EEG sigma (10-15 Hz) activity during sleep exhibits infraslow oscillations (ISO) with a period of 50 s. However, a detailed analysis of the ISO of individually identified sleep spindles is not available. NEW METHOD:We investigated basic properties of ISO during baseline ...

journal_title：Journal of neuroscience methods

authors： Lázár ZI,Dijk DJ,Lázár AS

更新日期：2019-03-15 00:00:00

abstract：BACKGROUND:During slow-wave sleep the electroencephalographic (EEG) and local field potential (LFP) recordings reveal the presence of large amplitude slow waves. Systematic extraction of individual slow waves is not trivial. NEW METHOD:In this study, we used the neural network pattern recognition to detect individual ...

journal_title：Journal of neuroscience methods

authors： Bukhtiyarova O,Soltani S,Chauvette S,Timofeev I

更新日期：2019-03-15 00:00:00

abstract：BACKGROUND:Although they form a unitary phenomenon, the relationship between extracranial M/EEG and transmembrane ion flows is understood only as a general principle rather than as a well-articulated and quantified causal chain. METHOD:We present an integrated multiscale model, consisting of a neural simulation of tha...

journal_title：Journal of neuroscience methods

authors： Rosen BQ,Krishnan GP,Sanda P,Komarov M,Sejnowski T,Rulkov N,Ulbert I,Eross L,Madsen J,Devinsky O,Doyle W,Fabo D,Cash S,Bazhenov M,Halgren E

更新日期：2019-03-15 00:00:00

abstract：:Sleep is an innate behavior conserved in all animals and, in vertebrates, is regulated by neuronal circuits in the brain. The conventional techniques of forward and reverse genetics have enabled researchers to investigate the molecular mechanisms that regulate sleep and arousal. However, functional interrogation of ge...

journal_title：Journal of neuroscience methods

authors： Yamaguchi H,de Lecea L

更新日期：2019-03-15 00:00:00

abstract：BACKGROUND:The input signals of electroencephalography (EEG) based brain computer interfaces (BCI) are extensively acquired from scalp with a multi-channel system. However, multi-channel signals might contain redundant information and increase computational complexity. Furthermore, using only effective channels, rather...

journal_title：Journal of neuroscience methods

authors： Aydemir O,Ergün E

更新日期：2019-02-01 00:00:00

abstract：:Barckground Alzheimer's disease (AD) is mainly caused by cellular loss and dysfunction of the basal forebrain cholinergic neurons and cholinergic axons in the cortex leading to slowly progressive decline in learning and memory performance. Unfortunately, no definitive treatment to halt neural cell loss exists to date....

journal_title：Journal of neuroscience methods

authors： Mendivil-Perez M,Velez-Pardo C,Jimenez-Del-Rio M

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND:Controlled cortical impact (CCI) has emerged as one of the most flexible and clinically applicable approaches for the induction of traumatic brain injury (TBI) in rodents and other species. Although this approach has been shown to model cognitive and functional outcomes associated with TBI in humans, recent ...

journal_title：Journal of neuroscience methods

authors： Sellappan P,Cote J,Kreth PA,Schepkin VD,Darkazalli A,Morris DR,Alvi FS,Levenson CW

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND:Chronic recordings with multi-electrode arrays are widely used to study neural networks underlying complex primate behaviors. Most of these systems are designed for studying neural activity in the cortical hemispheres resulting in a lack of devices being capable of simultaneously recording from ensembles of ...

journal_title：Journal of neuroscience methods

authors： Pomberger T,Hage SR

更新日期：2019-01-01 00:00:00

abstract：:Classification of spoken word-evoked potentials is useful for both neuroscientific and clinical applications including brain-computer interfaces (BCIs). By evaluating whether adopting a biology-based structure improves a classifier's accuracy, we can investigate the importance of such structure in human brain circuitr...

journal_title：Journal of neuroscience methods

authors： Na Y,Choi I,Jang DP,Kang JK,Woo J

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Schizophrenia is a predominant product of pathological alterations distributed throughout interconnected neural systems. Designing new objectively diagnostic methods are burning questions. Dynamical functional connectivity (DFCs) methodology based on fMRI data is an effective lever to investigate changeabili...

journal_title：Journal of neuroscience methods

authors： Chen B

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Deviant stimuli within a standard, frequent stimulus train induce a cortical somatosensory mismatch response (SMMR). The SMMR reflects the brain's automatic mechanism for the detection of change in a somatosensory domain. It is usually elicited by electrical stimulation, which activates nerve fibers and rece...

journal_title：Journal of neuroscience methods

authors： Hautasaari P,Kujala UM,Tarkka IM

更新日期：2019-01-01 00:00:00